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CIE Nov 2015 v3 Paper 4 Q9
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![20 Prodrugs are compounds that are inactive, but are easily converted in the body to the active drug by enzyme hydrolysis. Compound W is a prodrug. CH3 PMT H2N NH2 O W (a) Complete the molecular formula for W. C H34N O [1] (b) Compound W contains a benzene ring in its structure. Name three other functional groups in W.[2] (c) (i) On the diagram above, use an arrow to indicate the bond that would be hydrolysed. [1] (ii) Draw the structures of the likely products of the enzyme hydrolysis of compound W. (d) What features of the molecule W make it water soluble? Explain your answer.[2] [Total: 8] [2] To avoid the issue of disclosure of answer-related information to candidates, all copyright acknowledgements are reproduced online in the Cambridge International Examinations Copyright Acknowledgements Booklet. This is produced for each series of examinations and is freely available to download at www.cie.org.uk after the live examination series.UCLES 2015 9701/43/O/N/15<br />](https://learnah.org/wp-content/uploads/2018/08/November_2015_v3_QP_-_Paper_4_CIE_Chemistry_A-level_9.jpg)
![Page 11 Mark Scheme Syllabus Paper Cambridge International A LevelOctober/November 2015 9701 43 Question Marking Point (ii) chemical type of number of splitting pattern PMT Marks Total Marks shift/ ppm 1.0 2.3 3.7 proton(s) protons CH3-R CH2CO CH3O (iii) structure / name of methyl propanoate H3C CH2 (a) C24(H34)N2O3 (b) ketone amine ester triplet quartet singlet CH3Cambridge International Examinations 2015 [Total: 11]<br />
Pa age 12 Cam mbr ridg e In nter M Mar rking g Po oint Qu esti on ( (c) (i) Mar rk S Sche eme nati iona al A A Le evelO Octo ober r/No ovem mbe er 2 2015 5 PMT P Pap per Sy yllab bus 9 970 43 Maarks s TTotal l Ma arks s (ii) ( (d) h hyd roge en b bond ding g or ion -dip pole forc ces [To tal: 8] i invo olvin ng lo one pair r on N a atom ms, or lo one pai r on n O atom ms, or N NH2 2 gro oups s, or r CO O2 g rou ps, or C C=O O gro oups s, w with h wa aterCa ambr ridge e Int terna ation nal E Exam mina ation ns 20 015<br />](https://learnah.org/wp-content/uploads/2018/08/November_2015_v3_MS_-_Paper_4_CIE_Chemistry_A-level_9-0.jpg)
